Aesthetics is no longer moving in a straight line. It is expanding, colliding, and evolving into something much bigger than beauty alone.
This is no longer about choosing a treatment and hoping it works. The industry is moving toward a model where outcomes can be anticipated, care is tailored to the individual, and aesthetics, wellness, and longevity are starting to operate as one connected system.
In this episode of The Dr. Randi Show, Dr. Randi sits down with Anthony Serhan, founder and CEO of Pink Sky and a longtime industry insider with more than two decades across pharma, aesthetics, and device innovation, including executive leadership at Merz Aesthetics.
From what he’s seeing across the market, this is not incremental change. It’s a rethinking of how patients are treated, how clinics operate, and how results are delivered.
Dr. Randi and Anthony break down:
• The rise of peptides, regenerative treatments, and GLP-1s and how they are changing patient expectations
• How genetic and biomarker testing will predict which treatments work for you before you spend the time or money
• What exosomes, NAD, and hair restoration signal about where real demand is heading
• The emergence of next-level therapies designed to reset and recharge the body, from advanced blood treatments to oxygen-based performance therapies
• Why treatment stacking is becoming the new standard for delivering impactful results
This is a clear look at where the industry is going from someone who has helped build it and knows what’s coming next.
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Episode FAQ
What is The Dr. Randi Show episode with the founder of Pink Sky about?
This episode of The Dr. Randi Show features Anthony Serhan, founder and CEO of Pink Sky, who spent more than two decades across pharma, aesthetics, and device innovation, including senior leadership at Merz Aesthetics. The through-line of the conversation is what Serhan calls the collision of aesthetics and wellness, two categories he sees merging into one. He and host Dr. Randi Boyette explore regenerative and longevity treatments, peptides and GLP-1s, personalized genetic testing, exosomes, NAD, blood-filtering therapies, hair restoration, and how AI is reshaping the patient experience.
Why are aesthetics and wellness converging into one market?
On The Dr. Randi Show, the guest describes aesthetics and wellness as no longer parallel markets but colliding forces, which is how Anthony Serhan would headline this moment in the industry. He points to the wellness sector, with peptides and GLP-1s, merging with traditional aesthetics. Using market-maturity stages such as emergence, acceleration, and saturation, he characterizes the current period as a reinvention driven by that convergence, bringing together very different patients and consumers. He notes that only about 4% of adults have ever had or considered an aesthetic injection, while roughly 20% engage with the wellness side, which is where he sees the two audiences beginning to overlap.
What are regenerative and pre-generative longevity treatments in aesthetics?
Anthony Serhan explains on the episode that regenerative has become a defining buzzword, with treatments aimed at helping the body restore itself. He distinguishes between patients seeking regeneration and those pursuing what he calls a pre-generative approach, preserving what they have before decline sets in, under the broader banner of longevity. As one example, the guest points to biostimulators, such as calcium hydroxyapatite and PLLA based products, that prompt the body to produce its own collagen and elastin. He frames this as a personal interest as much as a professional one, describing himself as being at an age that finds regeneration especially appealing.
How are peptides and GLP-1s being used in aesthetics and longevity?
The guest, Anthony Serhan, sees peptides and GLP-1s as central to the future of aesthetics and wellness, and says they are not going anywhere. He expects more options as regulators clear additional peptides for use, which he believes will lead to treatment stacking and cycling tailored to each patient, since not everyone needs the same compounds (he references GHK-Cu and BPC-157 as examples). Serhan notes that weight loss from GLP-1s often leads patients to seek facial volume restoration, which is where biostimulators come in. He also stresses that providers should confirm where peptides are sourced, and that emerging treatment protocols are adding welcome clarity to a confusing market.
Can genetic and biomarker testing personalize aesthetic and wellness treatments?
Anthony Serhan calls personalized treatment guided by genetics and biomarkers the holy grail of aesthetics and wellness. On the episode, he describes methylation testing, which maps how a person’s genes respond to specific ingredients and treatments, going beyond ancestry-style DNA tests. As an example, the guest cites minoxidil, noting that 38% of the population cannot methylate it, so a simple cheek swab could tell someone whether a product will work before they buy it. He also describes baselining the biological age of a person’s collagen and elastin, so a provider can build a care plan intended to improve those markers over time.
Are exosomes living up to the hype in skincare and aesthetics?
On The Dr. Randi Show, the guest says exosome technology has made major advances and that the science keeps improving. Anthony Serhan points to research into how the source of exosomes, described as tiny messengers, influences which genes they activate and how outcomes can be maximized. He no longer considers exosomes merely emerging, and expects to see them increasingly incorporated into skincare, where patients are reporting strong results.
How does NAD work in longevity and skincare, and what is NMN?
Anthony Serhan shares on the episode that he has not tried NAD by injection but has used skincare containing NMN, the last component in the cycle that helps the body create its own endogenous NAD. The guest notes that some products deliver NAD precursors through the mucosa at the top of the mouth, offering an oral option for people who prefer to avoid injections. He explains that applying NAD directly to the skin does not accomplish much on its own, whereas supporting the body’s own production, or using an exogenous source, is where he sees real promise, and he expects NAD skincare to grow quickly.
What is EBOO, and how is hyperbaric oxygen being used for longevity?
Anthony Serhan describes EBOO, which he calls the human oil change, as a therapy that draws blood from one arm, passes it through a machine that applies UV light and filters it through an FDA-cleared dialysis-style filter, hyper-oxygenates it through ozonation, and returns it through the other arm. On the episode, the guest says the process helps filter out heavy metals and microplastics, and that patients, including some dealing with long COVID and others who are simply health focused, report feeling great. He adds that hyperbaric oxygen is having a resurgence as chambers improve, with some people even installing them at home.
Why is hair restoration becoming a bigger category in aesthetics?
The guest, Anthony Serhan, links rising demand for hair restoration to GLP-1s, TRT, and HRT, noting that more than half of GLP-1 users report some hair loss. On the episode, he describes practices moving toward a holistic approach that tests which treatments will work best for an individual, then pairs medications, ingredients, shampoos, and energy-based devices accordingly, rather than relying on a single solution. Serhan also shares that, to his surprise, women make up roughly 70% of the hair-restoration population, and welcomes that more solutions and open conversation now exist.
How is AI changing the way aesthetic treatments are delivered?
Anthony Serhan calls AI a game changer and says practices that adopt it early will have an edge. On The Dr. Randi Show, the guest describes AI handling patient questions and booking even when a clinic is closed, effectively drawing on a provider’s expertise around the clock, along with AI-powered calling and AI search engines that patients increasingly use to find providers instead of traditional search. He frames AI as a tool for education, access, and convenience, joking that if you cannot beat the robots, you might as well work with them.
