In this episode of The Dr. Randi Show, Dr. Randi Boyette welcomes back Dr. Steven Dayan for a dynamic conversation about the forces reshaping aesthetic medicine and the changing definition of a successful result.
One of the industry’s most respected facial plastic surgeons, researchers, and educators, Dr. Dayan connects the worlds of surgery, skincare, psychology, neuroscience, artificial intelligence, and longevity. He explains why aesthetic medicine is expanding its focus to include how appearance influences confidence, trust, attraction, relationships, and overall quality of life.
They discuss:
- Why aesthetics, wellness, and longevity are coming together
- How artificial intelligence is influencing patient decisions
- What patients should understand about today’s surgical trends
- Why confidence and quality of life may become measurable treatment outcomes
- How XOMD is advancing the field of neurocosmetic skincare
- Where aesthetic medicine is headed over the next five years
From rhinoplasty, facelifts, and skin quality to the skin-brain connection and the subconscious signals that shape human attraction, Dr. Dayan offers a powerful look at what is coming next and why the future of aesthetics will be about far more than appearance.
Dr. Dayan also joins The Dr. Randi Show Expert Council as a founding member, bringing his experience, research, and perspective to the conversations that will help shape the future of the industry.
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Sponsored by NewBeauty 💄
Episode FAQ
What is XOMD mood skincare, and what does this episode of The Beauty Scene cover?
In this episode of The Beauty Scene on The Dr. Randi Show, host Dr. Randi Boyette talks with facial plastic surgeon and New York Times bestselling author Dr. Steven Dayan about XOMD, which he describes as the first mood skincare line. Dr. Dayan shares how the line is designed to support both skin health and emotional wellbeing, the science he says sits behind it, what his clinical testing showed, and where he believes aesthetic medicine is heading. He also discusses his approach to high-profile clients and offers his take on Kris Jenner’s widely discussed facelift.
What inspired the creation of the XOMD mood skincare line?
On this episode of The Dr. Randi Show, Dr. Dayan says that over 25 years in practice he came to believe that making people feel beautiful is more about emotion than physical perfection, and that roughly 70 percent of his daily work is treating how a patient feels rather than their appearance. He shares that this view, shaped by his background in evolutionary biology, psychology, and philosophy and years of teaching a science of beauty course, led him and his partner Dr. Sabrina Fabi to formulate XOMD from scratch rather than lend his name to an existing brand. He describes the line as a deeply personal project built around their research and passion.
How does XOMD work, and what is the OX Factor formula?
Dr. Dayan explains on the episode that XOMD is built around a proprietary blend he calls the OX Factor, which combines three parts. He describes a jasmine derivative meant to stimulate receptors in the skin, phospholipids intended to support skin quality, and a pheromone. He points to what he calls the skin brain axis, the idea that skin and brain communicate, and says the formula uses a botanical that mimics oxytocin to play off that hormone’s mood related effects rather than relying on a single active ingredient. These are the mechanisms he describes, framed as the thinking behind the product.
Does XOMD contain actual oxytocin?
No. On the episode, Dr. Dayan is clear that XOMD does not contain oxytocin. He says a common question is whether the product includes the hormone, and that it does not. Instead, he explains, the formula uses a botanical that is meant to mimic and play off oxytocin’s effects at the skin level rather than delivering the hormone itself.
What did the XOMD clinical trial find?
Dr. Dayan says XOMD was tested in a double blind, placebo controlled, randomized trial, which he notes is unusually rigorous for skincare. He reports that in his study skin quality and radiance improved, that up to 86 percent of participants saw higher confidence levels over four to eight weeks, and that participants projected stronger first impressions across eight categories compared with placebo. He also shares that, using a validated scale, women who used XOMD for eight weeks reported improved sexual satisfaction in 18 of 20 categories, about 90 percent, while the placebo group showed no comparable effect. These are the outcomes he reported from his trial, and individual results can vary.
How soon do people notice results from XOMD?
On the episode, Dr. Dayan says that anecdotally some people in the trial began to feel better within about two weeks as they noticed a glow, though the study itself measured results at four and eight weeks. He reports that improvements appeared by four weeks and continued to build through eight weeks, and because the trial stopped at eight weeks he cannot say what would happen beyond that. He suggests people can expect to start feeling better about themselves and to notice a glow around the four week mark, while noting these reflect his study’s findings rather than a guarantee.
What is prosocial aesthetics, and where does the guest see aesthetic medicine heading?
Dr. Dayan describes prosocial aesthetics as a shift toward treatments that improve a person’s social life, not just their appearance. He frames it as a fourth order of outcomes, following mathematically perfect results, patient reported outcomes, and observer reported first impressions, and says future clinical trials may increasingly measure social benefits. He also shares that he sees aesthetic medicine, sexual health and wellness, and treatments like GLP-1 medications increasingly overlapping, and describes XOMD as helping to pioneer that direction. This reflects his personal perspective on the field.
What is next for XOMD?
On the episode, Dr. Dayan shares that XOMD is expanding, including a distribution agreement to reach dozens of countries across Europe and travel sizes in development, with hopes of adding Canada. He describes the line as a movement rather than just a product and says creating new markets is a major motivation. He also mentions his ongoing work as a US medical director within MedSpa Partners, a large aesthetic platform, continued surgery, and further clinical research alongside the skincare line.
What did the guest say about Kris Jenner’s facelift and the deep plane technique?
Asked about Kris Jenner’s widely discussed facelift, Dr. Dayan explains on the episode that a deep plane facelift is one way to approach the face and that the lift can be directed more vertically or more horizontally, so those directions are not mutually exclusive. He says it is hard to know exactly what was done, and speculates that chin augmentation, jawline refinement, or sculpting of the platysma muscle could contribute to a more defined result. He offers this as general commentary rather than knowledge of her specific procedure.
What has the guest learned from working with high-profile clients?
Dr. Dayan shares on the episode that working with high-profile clients has taught him that the most established A-list clients tend to be gracious and appreciative, while those still seeking that status can be more difficult. He also says appointments sometimes fall through when a publicist cancels or a client arrives under a false name. His main advice, which he passes on to younger colleagues, is to treat well known clients like any other patient, because bending the usual rules can
